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- 產(chǎn)品名稱(chēng)： Recombinant Human HDAC8 protein
- 產(chǎn)品貨號： CSP00474
- 貨期： 現貨
- 價(jià)格與訂購： 1800
- 數量：
庫存： 100
- 規格： 50μg 100μg 1mg
- 產(chǎn)品信息
- 如何訂購
概述（Summary）
英文全稱(chēng)
Recombinant Human HDAC8 protein
純度（Purity）
>90% as determined by SDS-PAGE
內毒素（Endotoxin level）
Please contact with the lab for this information.
蛋白構建（Construction）
A DNA sequence encoding the human HDAC8 (Met1-Val377) was fused with His tag
Accession #
Q9BY41
表達宿主（Host）
E.coli
種屬（Species）
Homo sapiens (Human)
預測分子量（Predicted Molecular Mass）
40.75 kDa
制劑（Formulation）
Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
運輸方式（Shipping）
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
穩定性&儲存（Stability &Storage）
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
復溶（Reconstitution）
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
背景（Background）
背景介紹
Histone deacetylase 8, also known as HDAC8 and HDACL1, is a nucleus and cytoplasm protein which belongs to thehistone deacetylase family and HD type 1 subfamily. Histone deacetylases (HDACs) are a growing family of enzymes implicated in transcriptional regulation by affecting the acetylation state of core histones in the nucleus of cells.HDAC8 / HDACL1 is weakly expressed in most tissues. It expressed at higher level in heart, brain, kidney and pancreas and also in liver, lung, placenta, prostate and kidney. HDAC8 / HDACL1 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones ( H2A, H2B, H3 and H4 ). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC8 / HDACL1 may play a role in smooth muscle cell contractility. HDAC8 / HDACL1 may be a potential drug target for neuroblastoma differentiation therapy using selective inhibitors, avoiding unspecific side effects.
分子別名（Alternative Names）
Histone deacetylase 8,HD8.
Note
For research use only .
地 址：
產(chǎn)品銷(xiāo)售：
E - mail ：
郵 編：
Amily
