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  • 產(chǎn)品名稱(chēng): Recombinant Human HIF-1β protein
  • 產(chǎn)品貨號: CSP00476
  • 貨期: 現貨
  • 價(jià)格與訂購: 1800
  • 數量:
    庫存: 100
  • 規格: 50μg 100μg 1mg
  • 產(chǎn)品信息
  • 如何訂購
    概述(Summary)
    英文全稱(chēng)
    Recombinant Human HIF-1β protein
    純度(Purity)
    >90% as determined by SDS-PAGE
    內毒素(Endotoxin level)
    Please contact with the lab for this information.
    蛋白構建(Construction)
    A DNA sequence encoding the human HIF-1β (Met1-Ser348) was fused with His tag
    Accession #
    P27540
    表達宿主(Host)
    E.coli
    種屬(Species)
    Homo sapiens (Human)
    預測分子量(Predicted Molecular Mass)
    38.71 kDa
    制劑(Formulation)
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    運輸方式(Shipping)
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
    穩定性&儲存(Stability &Storage)
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    復溶(Reconstitution)
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
    背景(Background)
    背景介紹
    Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia (By similarity). The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription.
    分子別名(Alternative Names)
    Aryl hydrocarbon receptor nuclear translocator,ARNT protein,Class E basic helix-loop-helix protein 2,bHLHe2,Dioxin receptor, nuclear translocator,Hypoxia-inducible factor 1-beta,HIF-1-beta,HIF1-beta.
    Note
    For research use only .