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- 產(chǎn)品名稱(chēng)： Recombinant Human THOP1 protein
- 產(chǎn)品貨號： CSP01380
- 貨期： 現貨
- 價(jià)格與訂購： 1800
- 數量：
庫存： 100
- 規格： 50μg 100μg 1mg
- 產(chǎn)品信息
- 如何訂購
概述（Summary）
英文全稱(chēng)
Recombinant Human THOP1 protein
純度（Purity）
>90% as determined by SDS-PAGE
內毒素（Endotoxin level）
Please contact with the lab for this information.
蛋白構建（Construction）
A DNA sequence encoding the human THOP1 (Asn451-Thr597) was fused with His tag
Accession #
P52888
表達宿主（Host）
E.coli
種屬（Species）
Homo sapiens (Human)
預測分子量（Predicted Molecular Mass）
18.62 kDa
制劑（Formulation）
Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
運輸方式（Shipping）
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
穩定性&儲存（Stability &Storage）
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
復溶（Reconstitution）
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
背景（Background）
背景介紹
THOP1, also known as Thimet oligopeptidase 1, Thimet oligopeptidase, EC 3.4.24.15, or EP24.15, is a zinc(II) endopeptidase implicated in the processing of numerous physiological peptides. As an intracellular enzyme, highly expressed in the brain, kidneys and neuroendocrine tissue, THOP1 has been proposed to metabolize peptides within cells, thereby affecting antigen presentation and G protein-coupled receptor signal transduction. Its substrates is gonadotrophin-releasing hormone (GnRH), an important hypothalamic hormone that regulates the synthesis and release of oestradiol and facilitates female sexual behaviour. THOP1 against toxic effects of Abeta in the early stages of Alzheimer disease (AD) pathology, and suggest that the observed increase in THOP1 expression might be part of a compensatory defense mechanism of the brain against an increased Abeta load.
分子別名（Alternative Names）
Thimet oligopeptidase,Endopeptidase 24.15,MP78.
Note
For research use only .
地 址：
產(chǎn)品銷(xiāo)售：
E - mail ：
郵 編：
Amily
